Applications: Bacillus subtilis, liposomes from traditional Chinese medicine, yeast, astaxanthin extraction from Haematococcus pluvialis.
Microfluidic homogenization technology enables nanoscale precision dispersion and highly efficient encapsulation, making it ideally suited for the nanoscale preparation of biopharmaceuticals such as liposomes and mRNA vaccines, thereby ensuring the quality stability and batch-to-batch consistency of high-value-added biopharmaceuticals.
Applications: Bacillus subtilis, liposomes from traditional Chinese medicine, yeast, astaxanthin extraction from Haematococcus pluvialis.
Pure physical process with no impurities; precisely controls cell disruption while preserving active ingredients. Improves product yield by 15%, suitable for high-standard applications.
Adjustable parameters; 40% higher efficiency than conventional homogenizers. Meets targets within fewer cycles, with >98% batch consistency.
Self-developed core components ensure stable operation; 30% lower energy consumption vs traditional systems, with full-process technical support.
Micro-jet shearing produces finer particles, narrower distribution, and improved activity retention. Suitable for tough cell-wall microbes (e.g., Bacillus subtilis) and multiple strains (e.g., lactic acid bacteria, actinomycetes).
Bacillus subtilis is widely used in food, feed, fermentation, and agriculture. Cell disruption efficiency, activity retention, and dispersion uniformity directly impact product efficacy, quality, cost, and scalability.
Bacillus subtilis has a thick cell wall, which easily leads to incomplete cell wall disruption, loss of active ingredients, and uneven dispersion during deep processing, resulting in decreased product efficacy and a low yield.
1. Low efficiency (30–40%), poor cell wall penetration
2. High heat → activity degradation
3. Risk of contamination, poor consistency
4. Not scalable; >30% higher downstream costs
5. High energy consumption
1. Small-scale only, not for mass production
2. Local overheating damages activity
3. Poor repeatability, cross-contamination risk
4. Batch processing slows delivery
1. Plunger structure, insufficient pressure
2. Multiple cycles → high energy, unstable results
3. Over-disruption damages actives
4. Large batch variation, quality risk
We provide customized microfluidic high pressure homogenization for efficient cell disruption. Pure physical processing generates strong shear, impact, and cavitation, enabling effective cell wall breakage while preserving activity through precise parameter control.
From process adaptation and parameter optimization to production line design, we provide one-stop customization services.
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