Pilot-Scale Microfluidic Homogenizer

Precisely homogenizes materials from micron to nanoscale, ensuring uniform particle distribution, consistent batches, and intact active ingredients.

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250L High Pressure Pilot Scale Homogenizer

HPW-250

Designed for pilot production, bridging lab R&D and full-scale manufacturing. Powered by a 37 kW motor with a hydraulic drive system for high efficiency and stable pressure, it easily handles high-viscosity and agglomerated materials. Integrated CIP/SIP allows on-site cleaning and sterilization, preventing blockages and ensuring stable, efficient operation.

Designed for pilot production, bridging lab R&D and full-scale manufacturing. Powered by a 37 kW motor with a hydraulic drive system for high efficiency and stable pressure, it easily handles high-viscosity and agglomerated materials. Integrated CIP/SIP allows on-site cleaning and sterilization, preventing blockages and ensuring stable, efficient operation.

Core Technology: The HPW-250’s core homogenization mechanism features a diamond-shaped interlocking chamber (available in Y or Z configurations), with internal fixed microchannels that ensure consistent and uniform particle size results across batches.

Homogenization Pressure: Utilizing a bidirectional pressurization design, the system achieves a maximum pressure of 60,000 psi (420 MPa) and is equipped with a high-definition touchscreen control system and a pressure data visualization interface.

Low Residual Volume and Sample Volume: Minimum sample volume of 3,000 mL with a residual volume of approximately 1 mL. The high-precision dual-valve channel design allows flexible switching between material inlet and outlet ports, minimizing material waste.

Sanitary-Grade Materials: All materials in contact with the product are GMP- and FDA-approved, including 316L and 17-4PH stainless steel, tungsten carbide, zirconia, and high-molecular-weight polyethylene.

Precise Temperature Control: Can be equipped with a sanitary-grade temperature control system to effectively lower material temperature and ensure activity.

Modular Design: Supports the addition of an intelligent overload protection system, online sampling interfaces, and data compliance recording (GMP/GLP), among other features.

Model: HPW-250
Working Pressure: 0–60,000 psi (420 MPa)
Processing Capacity: 200–250 L
Minimum Processing Volume: 3000 mL
Chamber Configuration: To be determined (Diamond secondary chamber + Diamond Y/Z main chamber)
Processing Flow Rate: 4 L/min
Power System: Hydraulic Drive System
Feed Temperature: <90°C
Power Input: 380 V
Power: 37 kW
Control System: Touchscreen control, supports program settings, data recording, and remote monitoring
Net Weight (kg): 1100KG
Dimensions (WxDxH) mm: To be determined

Unlike traditional mixing and shearing, the high pressure microfluidic homogenizer uses pressures up to 400 MPa to drive materials through precision diamond-interlocking microchannels. Supersonic jets generate shear, impact, and cavitation forces that efficiently refine materials to the nanoscale with exceptional uniformity, far exceeding conventional methods.

Applications

Nano-scale precise homogenization of biopharmaceuticals ensures controlled particle size while preserving bioactivity.

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Efficient dispersion and mass transfer of nano-suspensions and emulsions, reducing development time and energy consumption.

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Customized homogenization, dispersion, and stabilization for graphene, nano-ceramics, and metal slurries.

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Ultra-fine homogenization and stable emulsification improve texture and shelf-life of protein drinks and dairy products.

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Optimize electrode slurry homogenization to enhance battery energy density and lifespan while reducing material processing costs.

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Enhance nano-encapsulation and stability of active ingredients, improving efficacy and skin feel performance.

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Frequently asked questions

Powered by ultra-high-pressure micro-jet technology, this nano homogenizer uses precisely controlled supersonic jets to reduce particle size from micron to nano scale, ensuring uniform distribution, consistent batches, and preserved bioactivity.

The ultra-high-pressure micro-jet homogenizer uses pressures up to 400 MPa to drive materials through precision diamond-interlocking microchannels. Supersonic jets generate shear, impact, and cavitation forces that efficiently refine materials to the nanoscale with exceptional uniformity, far exceeding conventional methods.

  • Optimized particle size with superior uniformity
  • Higher efficiency with gentler processing
  • Stable performance with low maintenance costs
  • High hygienic standards and easy cleaning
  • Outstanding performance in high-end applications
  • Biopharmaceuticals (liposomes, mRNA delivery systems)
  • Chemical processing (nano suspensions, dispersions)
  • Advanced materials (graphene, nanomaterials)
  • Cosmetics (nano encapsulation, skincare formulations)
  • New Energy (solid-state electrolytes, nano-nickel powder)
  • Food & Beverage (nano emulsions, functional ingredients)

More than an equipment supplier, we are your process partner. From process diagnostics and parameter optimization to ongoing technical support, our nano-precision technology helps overcome R&D and production challenges, driving innovation and efficiency.