Leveraging its extensive expertise in ultra-high-pressure technology, JUNJIE has launched an industry-leading microfluidic high pressure homogenizer. This equipment utilizes core ultra-high-pressure microfluidic technology and is designed for pressures up to 420 MPa. Under ultra-high pressure, materials pass through micron-scale channels, where the shear forces generated by high-speed collisions and the cavitation effect enable homogenization from the micron to the nanometer scale. From the experimental model (HPW-10/20) to the pilot-scale model (HPW-250) and the mass-production model (HPW-500), the system supports linear scaling of process parameters, ensuring a smooth transition from R&D results to large-scale production. It provides comprehensive solutions for the dispersion and processing of nanoscale materials to universities, research institutes, and industries such as new materials, new energy, biopharmaceuticals, food, and chemicals.

JUNJIE Microfluidizer Working Principle

Unlike traditional shear mixing methods, the high pressure microfluidic homogenizer uses ultra-high pressure (up to 420 MPa) as the driving force to process materials at the nanoscale. The process is as follows:

  1. Pressurization & Injection: The material is pressurized and propelled at extremely high speed into the micro-channels of a specially designed diamond interaction chamber.
  2. Supersonic Jet Formation: The material forms a supersonic jet within the micro-channels.
  3. Triple Force Synergy: Through the combined action of high shear force generated by high-speed flow, frontal impact force from jet collision, and cavitation effects from the rapid formation and collapse of bubbles, the material is efficiently refined to the nanoscale with exceptional uniformity.

JUNJIE Microfluidizer Technical Advantages

1.Diamond Interaction Chamber Technology: The core homogenization component is made of diamond, with fixed micro-channels ensuring consistent and uniform particle size results across batches, along with high wear resistance.

2.Precise Temperature Control System: Can be equipped with a sanitary temperature control system (including heat exchangers, chillers, etc.) to effectively reduce material temperature and maintain the activity of heat-sensitive materials (e.g., bioactive proteins), with temperature control accuracy of ±1°C.

3.Sanitary Materials: All wetted parts are made of 316L stainless steel, tungsten carbide, zirconia, etc., compliant with GMP and FDA standards, ensuring hygiene and safety.

4.Intelligence & Compliance:

Equipped with an HD touchscreen control system supporting program setting, data logging, and remote monitoring.

Supports optional intelligent overload protection system (covering pressure, motor, and material clogging protection).

Supports GMP/GLP compliant data recording to meet strict traceability requirements in the pharmaceutical industry.

5. Modular Design: Supports optional add-ons such as online sampling ports and explosion-proof configurations for flexible expansion.

Benefits of JUNJIE Microfluidizer by Application Field

1. Biopharmaceuticals

  • Precise Particle Size Control & Activity Retention: For liposomes, mRNA vaccines, and other biologics, the nanoscale precision homogenization achieves accurate particle size control while maximizing the retention of bioactivity of large molecules, avoiding damage from heat or chemical agents in traditional processes.
  • Industrial-Scale Quality Consistency: The system is equipped with fully automatic CIP (Clean-in-Place) and SIP (Sterilize-in-Place) units, ensuring aseptic operation throughout the process. Batch-to-batch purity deviation is controlled within an extremely low range, solving the challenge of consistency.
  • Seamless Scale-Up: From lab-scale R&D to pilot testing and industrial production, the technology provides seamless transition, offering core technical support for the industrialization of monoclonal antibodies, recombinant proteins, and more.

2. Chemical Engineering

  • Significantly Enhanced Reaction Efficiency: The strong shear, high-speed impact, and cavitation effects generated by the diamond interaction chamber allow reactants to fully contact in an extremely short time, greatly improving dispersion compared to traditional stirring processes and accelerating reaction kinetics.
  • Precise Particle Size Control: For polymer synthesis, colloid dispersion, and catalyst preparation, precise pressure parameter adjustment enables accurate control of particle size from micron to nanoscale, effectively inhibiting particle agglomeration.
  • Reduced Production Costs: In polymer material synthesis, this technology significantly improves reaction conversion rates and narrows the molecular weight distribution, simplifying subsequent purification processes.

3. Materials Science

  • Nanoscale Uniform Dispersion: Raw material particles are precisely refined to the nanoscale and uniformly dispersed, effectively solving performance fluctuations caused by particle agglomeration and uneven distribution in traditional processes.
  • Optimized Microstructure: By altering the internal microstructure of materials, key performance indicators are significantly improved — for example, ceramic powder treated with this technology produces sintered ceramic substrates with notably higher density and greatly enhanced flexural strength; the interfacial bonding strength of polymer composites is also significantly increased.
  • Full-Chain Process Scale-Up: For functional materials such as graphene, nano-ceramics, and metal pastes, the technology provides a complete “homogenization-dispersion-stabilization” process chain, supporting seamless scale-up from lab to pilot to production, with customized solutions delivered within 7 days.

4. Food & Beverage

  • Efficient Sterilization & Nutrient Retention: Ultra-high pressure sterilization technology effectively eliminates harmful microorganisms without destroying heat-sensitive vitamins, active peptides, and other nutrients. Product shelf life is significantly extended without the need for preservatives.
  • Comprehensive Sensory Quality Improvement: Microfluidic homogenization refines particles to the nanoscale, resulting in significantly improved juice clarity and elimination of sedimentation; sauces, yogurt, and other products achieve much finer texture; off-flavors in plant-based protein beverages are notably reduced.
  • Enhanced Shelf-Life Stability: Ultra-fine refinement and stable emulsification technology significantly improve the taste and shelf-life stability of protein beverages, dairy products, and more.

5. New Energy

  • Optimized Electrode Slurry Quality: Active material particles are refined to the nanoscale, effectively reducing particle agglomeration. The active material, conductive agent, and binder form a three-dimensional uniformly distributed network structure within the slurry system.
  • Improved Battery Performance: The resulting battery electrodes exhibit significantly higher conductivity, notably extended charge-discharge cycle life, and optimized rate performance.
  • Suitable for Mass Production: The equipment features high processing capacity and is equipped with fully automatic feeding, discharging, and cleaning systems, perfectly meeting the large-scale, high-consistency production requirements of the new energy industry.

6. Cosmetics & Personal Care

  • Efficient Nano-Encapsulation of Active Ingredients: Functional active ingredients such as oils and plant extracts are refined to the nanoscale to form a stable emulsion system, significantly extending product shelf life without requiring excessive stabilizers.
  • Significantly Improved Skin Feel & Efficacy: Creams achieve a fine, silky texture with noticeably improved spreadability and a non-greasy feel; serums have enhanced transparency, and the penetration rate of active ingredients is effectively improved, solving the traditional challenge of active ingredients struggling to penetrate the stratum corneum.
  • Creating Differentiated High-End Products: Provides core technology empowerment for brands to develop high-end, efficacy-oriented products, enhancing brand premium.

JUNJIE Microfluidizer Service Support

While pursuing efficient production, JUNJIE also attaches great importance to environmental protection and energy conservation. The microfluidic homogenizer adopts an efficient and energy-saving power system, which reduces energy consumption and achieves a zero-emission green production model, which is in line with the current concept of sustainable development advocated globally. At the same time, the equipment is equipped with an advanced intelligent control system that can monitor and adjust working parameters in real time to ensure that every homogenization treatment can achieve the best results. The user-friendly interface design makes operation more convenient and greatly improves work efficiency.

JUNJIE knows that high-quality products are inseparable from professional service support. Therefore, we promise to provide every customer with a full range of services from technical consultation, installation and commissioning to after-sales maintenance, ensuring that any problems encountered by customers during use can be solved promptly and effectively. We are committed to establishing long-term and stable cooperative relationships with our customers, jointly exploring new areas of material homogenization, and promoting the continuous progress and innovation of industry technology.

Conclusion

JUNJIE microfluidic homogenizer is gradually reshaping the future of material homogenization with its excellent technical features, wide range of application fields, efficient and energy-saving production mode and professional service support. We believe that with the continuous efforts of JUNJIE Company, microfluidic homogenizer will become the trusted choice of more industry customers and jointly create a more brilliant tomorrow.

Tags: